Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523931 | 0.92 | ACE (0.52) | ACERENPREPDPP4DPP8 | |
| SCHEMBL7264396 | 0.90 | KDM4E (0.51) | ACEALDH1A1TSHRRENPREP | |
| SCHEMBL7273181 | 0.90 | ACE (0.50) | ACEALDH1A1CYP3A4TSHRREN | |
| SCHEMBL7271905 | 0.88 | ACE (0.49) | ACEALDH1A1TSHRRENPREP | |
| SCHEMBL7273358 | 0.88 | ACE (0.49) | ACEALDH1A1CYP3A4TSHRREN | |
| SCHEMBL11794997 | 0.88 | ACE (0.48) | ACEALDH1A1CYP3A4TSHRREN | |
| SCHEMBL11791864 | 0.87 | ACE (0.49) | ACEALDH1A1CYP3A4TSHRREN | |
| Hydrochloric Acid SCHEMBL10725183 | 0.86 | FKBP1A (0.47) | ACEFKBP1ADPP4DPP8 | |
| SCHEMBL7271844 | 0.86 | PRCP (0.53) | ACEFKBP1ACYP3A4TSHRREN | |
| SCHEMBL11585814 | 0.86 | ACE (0.49) | ACECYP3A4TSHRRENPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123444-A1 | 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |