SCHEMBL726440

SCHEMBL726440

COC1(c2ccccc2)Oc2cccc(O)c2C(=O)C1(O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
CYP3A4 P08684 4/20 0.32
CYP2C9 P11712 2/20 0.32
TXNRD1 Q16881 1/20 0.32
TXNRD3 Q86VQ6 1/20 0.32
TXNRD2 Q9NNW7 1/20 0.32
RIPK1 Q13546 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
ALOX15 P16050 3/20 0.31
MAPK1 P28482 2/20 0.31
CYP2C19 P33261 2/20 0.31
ADK P55263 1/20 0.30
KDM4E B2RXH2 1/20 0.30
AURKA O14965 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725961 0.86 MEN1 (0.31) MEN1KMT2ACYP3A4RIPK1ALOX15
SCHEMBL30689853 0.79 CA1 (0.39) CA1CA2CA7CA9MEN1
SCHEMBL3698500 0.79 CA1 (0.39) CA1CA2CA7CA9MEN1
SCHEMBL28970951 0.78 TXNRD1 (0.36) CA1CA2CA7CA9MEN1
SCHEMBL28524099 0.78 STK17B (0.36) CA1CA2CA7CA9MEN1
SCHEMBL27882641 0.73 CA1 (0.39) CA1CA2CA7CA9MEN1
SCHEMBL6239976 0.71 CYP3A4 (0.39) CA1CA2CA7CA9MEN1
SCHEMBL27660494 0.71 KDM4E (0.40) CA1CA2CA7CA9MEN1
SCHEMBL28410258 0.70 KDM4E (0.36) MEN1KMT2ACYP3A4ALOX15MAPK1
SCHEMBL27869068 0.69 AKT1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240301326-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt Benckiser Health Limited (GB) 2024-09-12 US claimed
EP-4373906-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2024-05-29 EP claimed
WO-2023002214-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2023-01-26 WO claimed
JP-4744081-B2 2011-08-10 JP claimed
EP-1429602-A4 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS UNIV RUTGERS (US) 2005-12-21 EP claimed
US-20050069598-A1 Methods for treating disorders using plant extracts RIBNICKY DAVID M (US) 2005-03-31 US claimed
JP-2005505544-A 2005-02-24 JP claimed
US-20040180800-A1 Cleaning and protecting composition with antioxidant and UV light resistance and method of use HOMECARE LABS, INC. 2004-09-16 US claimed
EP-1429602-A1 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2004-06-23 EP claimed
US-20030072822-A1 Methods for treating disorders using plant extracts RUTGERS, THE STATE OF UNIVERSITY OF NEW JERSEY 2003-04-17 US claimed
WO-2003020026-A1 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2003-03-13 WO claimed
US-20240301326-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt Benckiser Health Limited (GB) 2024-09-12 US disclosed
EP-4373906-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2024-05-29 EP disclosed
WO-2023002214-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2023-01-26 WO disclosed
EP-1784201-B1 PHYSIOLOGICALLY ACTIVE COMPOSITION AGAINST DIABETES PHYTOMEDICS INC (US) 2010-10-20 EP disclosed
US-20050069598-A1 Methods for treating disorders using plant extracts RIBNICKY DAVID M (US) 2005-03-31 US disclosed
US-20040180800-A1 Cleaning and protecting composition with antioxidant and UV light resistance and method of use HOMECARE LABS, INC. 2004-09-16 US disclosed
EP-1429602-A1 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2004-06-23 EP disclosed
US-20030072822-A1 Methods for treating disorders using plant extracts RUTGERS, THE STATE OF UNIVERSITY OF NEW JERSEY 2003-04-17 US disclosed
WO-2003020026-A1 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2003-03-13 WO disclosed