Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726440 | 0.70 | CA1 (0.35) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL3698500 | 0.64 | CA1 (0.39) | KDM4EALDH1A1HPGDHSD17B10TTR | |
| SCHEMBL30689853 | 0.64 | CA1 (0.39) | KDM4EALDH1A1HPGDHSD17B10TTR | |
| SCHEMBL27882641 | 0.64 | CA1 (0.39) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29287472 | 0.63 | PTGS2 (0.38) | KDM4EALDH1A1HPGDHSD17B10PTPN1 | |
| SCHEMBL3282386 | 0.63 | CA1 (0.38) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL4320359 | 0.63 | TTR (0.42) | KDM4EALDH1A1HPGDHSD17B10TTR | |
| SCHEMBL14336079 | 0.62 | PTPN1 (0.38) | KDM4EALDH1A1HPGDHSD17B10PTPN1 | |
| SCHEMBL6824008 | 0.62 | CA1 (0.42) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL28970951 | 0.61 | TXNRD1 (0.36) | MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111317732-A | Pharmaceutical composition for preventing nephropathy of CT contrast agent and preparation method thereof | 牡丹江医学院 | 2020-06-23 | — | — | CN | disclosed |