SCHEMBL7264684

SCHEMBL7264684

C=CCc1[nH]ccc1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1655686 0.76 GABRA1 (0.36)
SCHEMBL3208944 0.74
SCHEMBL7104653 0.74
SCHEMBL7908915 0.74
SCHEMBL2360008 0.74
SCHEMBL12971516 0.74
SCHEMBL8941721 0.70
SCHEMBL10427969 0.69 KMT2A (0.33)
SCHEMBL4798157 0.68 KEAP1 (0.37)
SCHEMBL10362110 0.68 GABRA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0213326-B1 2,5-DIMETHYL PYRROLE DERIVATIVES, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1991-03-06 EP claimed
WO-2003068738-A1 PYRROLE DERIVATIVES AS LIGANDS OF MELANOCORTIN RECEPTORS NEUROCRINE BIOSCIENCES, INC. (US) 2003-08-21 WO disclosed
EP-1121588-A1 MULTI-ARRAY MICROSYSTEM FOR CHEMICAL OR BIOLOGICAL ANALYSIS Commissariat à l'Energie Atomique (FR) 2001-08-08 EP disclosed
WO-2000022425-A1 MULTI-ARRAY MICROSYSTEM FOR CHEMICAL OR BIOLOGICAL ANALYSIS COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2000-04-20 WO disclosed
EP-0213326-B1 2,5-DIMETHYL PYRROLE DERIVATIVES, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1991-03-06 EP disclosed
US-4966901-A FOR TREATMENT OF ALZHEIMER*S DISEASE, LEARNING OR MEMORY PROBLEMS CASSELLA AKTIENGESELLSCHAFT (DE) 1990-10-30 US disclosed
EP-0346683-A1 Pyrrole derivatives, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1989-12-20 EP disclosed
US-4837225-A ENCEPHALOTROPIC AND PSYCHOTROPIC EFFECTS CASSELL AKTIENGESELLSCHAFT (DE) 1989-06-06 US disclosed
US-4785010-A AGING RESISTANCE OF HUMANS CASSELLA AKTIENGESELLSCHAFT (DE) 1988-11-15 US disclosed
EP-0213326-A1 2,5-Dimethyl pyrrole derivatives, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1987-03-11 EP disclosed
EP-0124067-B1 2-(AMINOALKYL)-PYRROLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1986-12-17 EP disclosed
EP-0124067-A1 2-(Aminoalkyl)-pyrrole derivatives, process for their manufacture and their use CASSELLA Aktiengesellschaft (DE) 1984-11-07 EP disclosed
US-4138292-A ENZYMES OR MICROORGANISMS IN A SULFATED POLYSACCHARIDE GEL TANABE SEIYAKU CO., LTD. (JP) 1979-02-06 US disclosed