Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265842 | 0.85 | KMT2A (0.50) | DPP4DPP8DPP7ACE | |
| SCHEMBL7266943 | 0.83 | DPP4 (0.56) | DPP4DPP8DPP7 | |
| SCHEMBL7265444 | 0.83 | PRCP (0.52) | DPP4DPP8DPP7POLBACE | |
| SCHEMBL7267072 | 0.81 | DPP4 (0.59) | DPP4PREPDPP8DPP7POLB | |
| SCHEMBL7273062 | 0.80 | DPP4 (0.52) | DPP4DPP8ACE | |
| SCHEMBL10333499 | 0.80 | TDP1 (0.50) | DPP4 | |
| SCHEMBL7273329 | 0.80 | L3MBTL1 (0.58) | DPP4PREPDPP8DPP7 | |
| SCHEMBL7272864 | 0.79 | L3MBTL1 (0.53) | DPP4PREPDPP8DPP7 | |
| SCHEMBL7272161 | 0.78 | L3MBTL1 (0.52) | DPP4PREPDPP8DPP7 | |
| SCHEMBL771117 | 0.77 | NPC1 (0.47) | BCHEDPP4PREPACEDUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340832-A | Prolinal derivatives useful for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-23 | — | — | US | claimed |
| EP-0268190-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | claimed |
| EP-0268190-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | claimed |
| US-5340832-A | Prolinal derivatives useful for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |