Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894370 | 0.76 | NOS2 (0.38) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL210388 | 0.76 | NOS2 (0.49) | TSHRALDH1A1 | |
| SCHEMBL3928876 | 0.76 | NOS2 (0.49) | TSHRALDH1A1 | |
| SCHEMBL210387 | 0.76 | NOS2 (0.49) | TSHRALDH1A1 | |
| SCHEMBL7265290 | 0.74 | TSHR (0.36) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL7265297 | 0.74 | TSHR (0.36) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| Hydrochloric Acid SCHEMBL29398667 | 0.74 | NOS2 (0.37) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| Hydrochloric Acid SCHEMBL4223453 | 0.74 | NOS2 (0.47) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL4223447 | 0.74 | NOS2 (0.47) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL29401714 | 0.74 | NOS2 (0.47) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579696-B1 | Comprising diaminobutyric acid having a gamma amino group and amino acid selected from cysteine, alanine and lysine; use in prevention and treatment of sepsis | PROMEGA CORPORATION | 2003-06-17 | — | — | US | disclosed |
| US-5998381-A | PROVIDING SUBJECT WITH BACTERIAL DISEASE WITH FIMBRIAE BINDING COMPOUND COMPRISING ANOMERIC MANNOSE, AN AROMATIC OR HETEROAROMATIC RING ATTACHED TO MANNOSE BY GLYCOSIDIC LINKAGE AND FUNCTIONAL GROUP PROVIDING MODIFICATION SITE | OPHIDIAN PHARMACEUTICALS, INC. (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0840619-A1 | PREVENTION AND TREATMENT OF SEPSIS | OPHIDIAN PHARMACEUTICALS, INC. (US) | 1998-05-13 | — | — | EP | disclosed |
| WO-1996040251-A1 | PREVENTION AND TREATMENT OF SEPSIS | OPHIDIAN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |