SCHEMBL7265393

SCHEMBL7265393

CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccccc4O)ccc3C(=O)O)ccc21

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RARG P13631 16/20 0.63
RARB P10826 13/20 0.63
RXRA P19793 4/20 0.63
RARA P10276 12/20 0.62
ABCB1 P08183 1/20 0.46
ABCC1 P33527 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793710 0.87 RARB (0.62) RARGRARBRXRARARAABCB1
SCHEMBL8350702 0.84 RARG (0.64) RARGRARBRXRARARAABCB1
SCHEMBL7794231 0.83 RARB (0.64) RARGRARBRXRARARA
SCHEMBL5846340 0.82 RARB (0.77) RARGRARBRXRARARAABCB1
SCHEMBL5846597 0.82 RARG (0.62) RARGRARBRXRARARA
SCHEMBL9551739 0.82 RARB (0.69) RARGRARBRXRARARAABCB1
SCHEMBL2919935 0.81 RARB (0.78) RARGRARBRXRARARAABCB1
SCHEMBL2917289 0.80 RARG (0.56) RARGRARBRXRARARA
SCHEMBL10549628 0.79 RARG (0.57) RARGRARBRXRARARAABCB1
SCHEMBL5845438 0.78 RARG (0.75) RARGRARBRXRARARAABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6649612-B1 Combating skin ageing and keratinization GALDERMA RESEARCH & DEVELOPMENT (FR) 2003-11-18 US disclosed