Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.62 |
| ▸ | RARG | P13631 | 10/20 | 0.62 |
| ▸ | RXRA | P19793 | 3/20 | 0.62 |
| ▸ | RARA | P10276 | 12/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794231 | 0.90 | RARB (0.64) | RARBRARGRXRARARAESR2 | |
| SCHEMBL7265393 | 0.87 | RARG (0.63) | RARBRARGRXRARARAABCB1 | |
| SCHEMBL7794229 | 0.83 | RARB (0.75) | RARBRARGRXRARARAABCB1 | |
| SCHEMBL27716421 | 0.83 | RARB (0.45) | RARBRARGRXRARARAESR2 | |
| SCHEMBL8346147 | 0.83 | RARB (0.69) | RARBRARGRXRARARA | |
| SCHEMBL24794240 | 0.80 | RARG (0.58) | RARBRARGRXRARARAPGR | |
| SCHEMBL24807991 | 0.80 | RARB (0.58) | RARBRARGRXRARARAALDH1A1 | |
| SCHEMBL2919935 | 0.80 | RARB (0.78) | RARBRARGRXRARARAABCB1 | |
| SCHEMBL7565094 | 0.80 | RARB (0.62) | RARBRARGRXRARARAABCB1 | |
| SCHEMBL7877006 | 0.78 | RARB (0.64) | RARBRARGRXRARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development (FR) | 1999-11-03 | — | — | EP | claimed |
| WO-1999010308-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT (FR) | 1999-03-04 | — | — | WO | claimed |
| CN-114957152-A | Synthetic method of benzoxazole compound | 湖南第一师范学院 | 2022-08-30 | — | — | CN | disclosed |
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | disclosed |
| EP-0952974-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development (FR) | 1999-11-03 | — | — | EP | disclosed |
| WO-1999010308-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT (FR) | 1999-03-04 | — | — | WO | disclosed |