Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.64 |
| ▸ | RARG | P13631 | 11/20 | 0.64 |
| ▸ | RXRA | P19793 | 4/20 | 0.64 |
| ▸ | RARA | P10276 | 13/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793710 | 0.90 | RARB (0.62) | RARBRARGRXRARARAALDH1A1 | |
| SCHEMBL7794229 | 0.87 | RARB (0.75) | RARBRARGRXRARARARXRB | |
| SCHEMBL6730349 | 0.87 | RARB (0.61) | RARBRARGRXRARARA | |
| SCHEMBL5846170 | 0.86 | RARB (0.60) | RARBRARGRXRARARABCL2L1 | |
| SCHEMBL5845438 | 0.86 | RARG (0.75) | RARBRARGRXRARARARXRB | |
| SCHEMBL8346147 | 0.86 | RARB (0.69) | RARBRARGRXRARARAALOX5 | |
| SCHEMBL2937025 | 0.84 | RARG (0.58) | RARBRARGRXRARARARXRB | |
| SCHEMBL7265393 | 0.83 | RARG (0.63) | RARBRARGRXRARARA | |
| SCHEMBL5846597 | 0.83 | RARG (0.62) | RARBRARGRXRARARA | |
| SCHEMBL5846339 | 0.82 | RARG (0.62) | RARBRARGRXRARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | disclosed |