Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.66 |
| ▸ | AGXT | P21549 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CHKA | P35790 | 4/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11851347 | 0.86 | PRMT6 (0.62) | PRMT6AGXTMEN1KMT2AKDM4E | |
| SCHEMBL28198974 | 0.83 | CHKA (0.56) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5227564 | 0.81 | SLC6A2 (0.48) | PRMT6AGXTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5301158 | 0.81 | CHKA (0.58) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL11849101 | 0.80 | PRMT6 (0.55) | PRMT6AGXTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16726976 | 0.80 | PRMT6 (0.63) | PRMT6AGXTMEN1KMT2AKDM4E | |
| SCHEMBL5095800 | 0.80 | AGXT (0.65) | PRMT6AGXTMEN1KMT2AKDM4E | |
| SCHEMBL15833077 | 0.80 | PRMT6 (0.63) | PRMT6AGXTMEN1KMT2AKDM4E | |
| SCHEMBL6268645 | 0.80 | PRMT6 (0.63) | PRMT6AGXTMEN1KMT2AKDM4E | |
| SCHEMBL113799 | 0.80 | AGXT (0.65) | PRMT6AGXTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566142-A1 | Inclusion complexes of optically active and racemic 1,4-dihydro pyridines with cyclodextrin derivates | LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. (SI) | 1993-10-20 | — | — | EP | claimed |
| EP-0207674-A2 | 1,4-Dihydropyridine derivatives, their preparation and their pharmaceutical use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | claimed |
| JP-6100537-A | — | — | None | — | — | JP | disclosed |
| US-5519012-A | CALCIUM ANTAGONISTS, CARDIOVASCULAR DISORDERS | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, D.D., LJUBLJANA (SI) | 1996-05-21 | — | — | US | disclosed |
| US-5519012-A | CALCIUM ANTAGONISTS, CARDIOVASCULAR DISORDERS | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, D.D., LJUBLJANA (SI) | 1996-05-21 | — | — | US | disclosed |
| JP-H06100537-A | INCLUSION COMPLEX OF OPTICALLY ACTIVE RACEMIC 1,4-DIHYDROPYRIDINE WITH METHYL-BETA-CYCLODEXTRIN OR OTHER CYCLODEXTRIN DERIVATIVE, PREPARATION OF OPTICALLY ACTIVE DIHYDROPYRIDINE AND ITS INCLUSION COMPLEX, MEDICINAL COMPOSITION CONTAINING SAME COMPLEX AND USE OF SAME COMPLEX | LEK TOVARNA FARMACEVTSKIH | 1994-04-12 | — | — | JP | disclosed |
| EP-0566142-A1 | Inclusion complexes of optically active and racemic 1,4-dihydro pyridines with cyclodextrin derivates | LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. (SI) | 1993-10-20 | — | — | EP | disclosed |
| EP-0566142-A1 | Inclusion complexes of optically active and racemic 1,4-dihydro pyridines with cyclodextrin derivates | LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. (SI) | 1993-10-20 | — | — | EP | disclosed |
| EP-0207674-A2 | 1,4-Dihydropyridine derivatives, their preparation and their pharmaceutical use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |