Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 12/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365035 | 0.97 | CMA1 (0.56) | CMA1CTSLKLK5FKBP1AACE | |
| SCHEMBL7336587 | 0.97 | CMA1 (0.56) | CMA1CTSLKLK5FKBP1AACE | |
| SCHEMBL7336591 | 0.97 | CMA1 (0.56) | CMA1CTSLKLK5FKBP1AACE | |
| SCHEMBL31185247 | 0.90 | CMA1 (0.52) | CMA1CTSLKLK5FKBP1AACE | |
| SCHEMBL7265619 | 0.90 | PREP (0.57) | CMA1CTSLKLK5FKBP1AACE | |
| SCHEMBL8366717 | 0.89 | CMA1 (0.65) | CMA1CTSLKLK5FKBP1A | |
| SCHEMBL7305436 | 0.89 | CMA1 (0.65) | CMA1CTSLKLK5FKBP1A | |
| SCHEMBL8366866 | 0.89 | CMA1 (0.51) | CMA1CTSLKLK5FKBP1AACE | |
| SCHEMBL11869876 | 0.88 | CYP3A4 (0.61) | CTSLFKBP1AACEKMT2AALDH1A1 | |
| SCHEMBL11869863 | 0.88 | CYP3A4 (0.61) | CTSLFKBP1AACEKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |