Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 15/20 | 0.65 |
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | CTRC | Q99895 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366717 | 1.00 | CMA1 (0.65) | CMA1ELANECTSLFKBP1AKLK5 | |
| SCHEMBL7285235 | 0.93 | CMA1 (0.60) | CMA1ELANECTSL | |
| SCHEMBL8365035 | 0.92 | CMA1 (0.56) | CMA1CTSLFKBP1AKLK5 | |
| SCHEMBL7336587 | 0.92 | CMA1 (0.56) | CMA1CTSLFKBP1AKLK5 | |
| SCHEMBL7336591 | 0.92 | CMA1 (0.56) | CMA1CTSLFKBP1AKLK5 | |
| SCHEMBL7265704 | 0.91 | PREP (0.61) | CMA1CTSLFKBP1AKLK5 | |
| SCHEMBL9699149 | 0.91 | PREP (0.61) | CMA1CTSLFKBP1AKLK5 | |
| SCHEMBL10882017 | 0.91 | PREP (0.61) | CMA1CTSLFKBP1AKLK5 | |
| SCHEMBL28545846 | 0.91 | PREP (0.61) | CMA1CTSLFKBP1AKLK5 | |
| SCHEMBL1992452 | 0.90 | FKBP1A (0.60) | CMA1ELANECTSLFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494071-B1 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5430025-A | Elastase-inhibiting peptides bearing a C-terminal trifluoromethylketone moiety | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5296591-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0494071-A2 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4691007-A | HUMAN LEUKOCYTE ELASTASE INHIBITORS | ICI AMERICAS INC. (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |
| US-4596789-A | Pharmaceuticals | ICI AMERICAS INC. (US) | 1986-06-24 | — | — | US | disclosed |
| EP-0124317-A2 | Proline derivatives | ICI AMERICAS INC. (US) | 1984-11-07 | — | — | EP | disclosed |