SCHEMBL8365035

SCHEMBL8365035

CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@@H]1C(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 12/20 0.56
CTSL P07711 1/20 0.53
FKBP1A P62942 3/20 0.52
KLK5 Q9Y337 1/20 0.52
ACE P12821 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7336587 1.00 CMA1 (0.56) CMA1CTSLFKBP1AKLK5ACE
SCHEMBL7336591 1.00 CMA1 (0.56) CMA1CTSLFKBP1AKLK5ACE
SCHEMBL7265463 0.97 CMA1 (0.54) CMA1CTSLFKBP1AKLK5ACE
SCHEMBL31185247 0.93 CMA1 (0.52) CMA1CTSLFKBP1AKLK5ACE
SCHEMBL7305436 0.92 CMA1 (0.65) CMA1CTSLFKBP1AKLK5
SCHEMBL8366717 0.92 CMA1 (0.65) CMA1CTSLFKBP1AKLK5
SCHEMBL8366866 0.92 CMA1 (0.51) CMA1CTSLFKBP1AKLK5ACE
SCHEMBL10882017 0.89 PREP (0.61) CMA1CTSLFKBP1AKLK5ACE
SCHEMBL9699149 0.89 PREP (0.61) CMA1CTSLFKBP1AKLK5ACE
SCHEMBL28545846 0.89 PREP (0.61) CMA1CTSLFKBP1AKLK5ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003057722-A2 CYCLIC TETRAPEPTIDE COMPOUND AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-07-17 WO disclosed