Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17902901 | 0.89 | YTHDC1 (0.79) | YTHDC1ADORA1ADORA3ADORA2AHTR2C | |
| SCHEMBL19010862 | 0.85 | YTHDC1 (0.73) | YTHDC1ADORA1ADORA3ADORA2AHTR2C | |
| SCHEMBL19049986 | 0.85 | YTHDC1 (1.00) | YTHDC1ADORA1ADORA3ADORA2AHTR2C | |
| SCHEMBL4649311 | 0.84 | YTHDC1 (0.72) | YTHDC1ADORA1ADORA3ADORA2AHTR2C | |
| SCHEMBL28433352 | 0.84 | YTHDC1 (0.74) | YTHDC1ADORA1ADORA3FLT3NPC1 | |
| SCHEMBL20104998 | 0.82 | YTHDC1 (0.72) | YTHDC1ADORA1ADORA3FLT3NPC1 | |
| SCHEMBL1713275 | 0.82 | YTHDC1 (0.79) | YTHDC1ADORA1ADORA3ADORA2AFLT3 | |
| SCHEMBL5442351 | 0.82 | YTHDC1 (0.78) | YTHDC1ADORA1ADORA3ADORA2AFLT3 | |
| SCHEMBL5442056 | 0.82 | YTHDC1 (0.67) | YTHDC1ADORA1ADORA3ADORA2AHTR2C | |
| SCHEMBL16549238 | 0.81 | YTHDC1 (0.77) | YTHDC1ADORA1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080604-A1 | DIHYDROISOXAZOLYL SUBSTITUTED TETRAHYDROFURAN COOMPOUNDS AS INTERMEDIATES IN THE PREPARATION OF 2-(PURIN-9-YL) - TETRAHYDROFURAN DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | disclosed |