Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29241906 | 0.85 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL27560087 | 0.83 | PAOX (0.48) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL28460206 | 0.81 | HAO1 (0.44) | ALDH1A1HAO1TSHR | |
| SCHEMBL28900147 | 0.79 | TDP1 (0.36) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL14335056 | 0.78 | KDM4E (0.46) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL874717 | 0.78 | KDM4E (0.46) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL26136419 | 0.78 | HAO1 (0.50) | ALDH1A1HAO1TSHR | |
| SCHEMBL1683265 | 0.77 | KDM4E (0.56) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL5574000 | 0.77 | — | — | |
| SCHEMBL28257446 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003091252-A1 | SPIROBARBITURIC ACID DERIVATIVES USEFUL AS INHIBITORS OF MATRIX METALLOPROTEASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-06 | — | — | WO | claimed |