Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335056 | 1.00 | KDM4E (0.46) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL5574000 | 0.95 | — | — | |
| Phosphine SCHEMBL28295591 | 0.92 | KDM4E (0.48) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| Cyclohexane SCHEMBL11698850 | 0.88 | KDM4E (0.44) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL28257446 | 0.84 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL28427478 | 0.83 | KDM4E (0.62) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL10936077 | 0.81 | KDM4E (0.55) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL26967576 | 0.81 | KDM4E (0.55) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL29241906 | 0.79 | KDM4E (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL7266153 | 0.78 | KDM4E (0.40) | KDM4EKDM6BKDM5CEGLN1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143035-B2 | Pantothenate kinase overexpression and pantothenic acid supplementation in actinomycetes | RICE UNIVERSITY (US) | 2012-03-27 | — | — | US | disclosed |