SCHEMBL7266299

SCHEMBL7266299

O=CC(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.54
TAAR1 Q96RJ0 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP1A2 P05177 1/20 0.48
ALPI P09923 1/20 0.45
PKM P14618 1/20 0.45
PTGS1 P23219 1/20 0.45
XIAP P98170 1/20 0.45
SLC7A5 Q01650 1/20 0.45
SLC6A2 P23975 2/20 0.44
MAOA P21397 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
MDM2 Q00987 1/20 0.43
ADH1B P00325 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27264418 0.88 SLC6A3 (0.53) EPHX1TAAR1MEN1KMT2ACYP1A2
SCHEMBL19812667 0.87 EPHX1 (0.47) EPHX1TAAR1MEN1KMT2ACYP1A2
SCHEMBL27309457 0.87 TRPA1 (0.48) EPHX1TAAR1MEN1KMT2ACYP1A2
SCHEMBL1774298 0.87 TAAR1 (0.48) EPHX1TAAR1MEN1KMT2ACYP1A2
SCHEMBL7266830 0.85 ACE (0.51) EPHX1TAAR1MEN1KMT2ACYP1A2
SCHEMBL12249323 0.85 ACE (0.51) EPHX1TAAR1MEN1KMT2ACYP1A2
SCHEMBL1546515 0.83 TAAR1 (0.46) EPHX1TAAR1MEN1KMT2ASLC6A2
SCHEMBL253605 0.83 EPHX1 (0.44) EPHX1TAAR1MEN1KMT2ACYP1A2
SCHEMBL19812642 0.83 EPHX1 (0.44) EPHX1TAAR1MEN1KMT2ACYP1A2
SCHEMBL28369667 0.83 CYP1A2 (0.44) EPHX1TAAR1MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613746-A Directably modified hexabenzo-metal organic framework, and preparation method and application thereof 南开大学 2025-03-14 CN claimed
CN-113817140-B Dendritic polymer and preparation method thereof 中电科芯片技术(集团)有限公司 2024-07-02 CN claimed
CN-115160102-B Preparation method of gem dihalide 上海珂华生物科技有限公司 2024-02-06 CN claimed
EP-0560267-B1 Isosteric antiherpes peptide derivatives BOEHRINGER INGELHEIM CA LTD (CA) 1998-08-19 EP claimed
EP-0767671-A1 METHOD OF COMBATING ACYCLOVIR-RESISTANT HERPES SIMPLEX VIRAL INFECTIONS BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1997-04-16 EP claimed
US-5574015-A Isosteric antiherpes peptide derivatives BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1996-11-12 US claimed
JP-H08507760-A 1996-08-20 JP claimed
US-5476841-A Inhibitors of herpes viral ribonucleotide reductase BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1995-12-19 US claimed
WO-1994025046-A1 METHOD OF COMBATING ACYCLOVIR-RESISTANT HERPES SIMPLEX VIRAL INFECTIONS BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-11-10 WO claimed
EP-0618226-A1 Inhibitors of herpes viral ribonculeotide reductase BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-10-05 EP claimed
WO-1994020528-A1 INHIBITORS OF HERPES VIRAL RIBONUCLEOTIDE REDUCTASE BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-09-15 WO claimed
WO-1993018056-A1 ISOSTERIC ANTIHERPES PEPTIDE DERIVATIVES BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-16 WO claimed
EP-0560267-A1 Isosteric antiherpes peptide derivatives BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP claimed
US-4829053-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-05-09 US claimed
US-4812555-A Peptides possessing renin inhibitory activity MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-03-14 US claimed
US-4721776-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-26 US claimed
CN-86105870-A Band 5-amino-2, the blood vessel tension peptide protoenzyme inhibitor of 5-two replacement-4-hydroxypentanoic acid bases 1987-03-11 CN claimed
EP-0212903-A2 Polypeptide derivatives containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues PFIZER INC. (US) 1987-03-04 EP claimed
CN-119912687-A Resin composition, additive thereof, cured film and electronic device 华为技术有限公司 2025-05-02 CN disclosed
US-4131623-A FROM DIHYDRO-1,3-OXAZINES, DECYCLIZATION BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL & MECHANICAL COLLEGE (US) 1978-12-26 US disclosed