Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330783 | 0.86 | MAPT (0.41) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL4823007 | 0.78 | ALDH1A1 (0.45) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL7528285 | 0.77 | MAPT (0.50) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL3139264 | 0.77 | MAPT (0.37) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL2168308 | 0.75 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL8821900 | 0.75 | MAPT (0.36) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL7258139 | 0.74 | POLB (0.50) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL5112777 | 0.74 | ALDH1A1 (0.45) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL3965014 | 0.74 | MAPT (0.52) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL3965007 | 0.74 | MAPT (0.52) | MAPTTP53ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099800-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BICYCLIC ANTIDIABETIC AGENTS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2003-12-04 | — | — | WO | disclosed |