Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8821900 | 0.98 | MAPT (0.36) | MAPTTP53KDM4EMAPK1USP2 | |
| SCHEMBL4330783 | 0.91 | MAPT (0.41) | MAPTTP53KDM4EMAPK1USP2 | |
| SCHEMBL7567358 | 0.81 | KDM1A (0.39) | MAPTTP53KDM4EMAPK1TDP1 | |
| Sulfuric Acid SCHEMBL6232322 | 0.79 | POLB (0.40) | MAPTTP53MAPK1HDAC1HDAC6 | |
| Sulfuric Acid SCHEMBL7586602 | 0.78 | POLB (0.39) | MAPTTP53MAPK1HDAC1HDAC6 | |
| Bromide SCHEMBL31588243 | 0.77 | TP53 (0.36) | MAPTTP53KDM4EMAPK1USP2 | |
| SCHEMBL7266307 | 0.77 | MAPT (0.49) | MAPTTP53KDM4EMAPK1HDAC1 | |
| Bromide SCHEMBL31588381 | 0.75 | KMT2A (0.54) | MAPTTP53KDM4EALOX15TDP1 | |
| Bromide SCHEMBL7401678 | 0.75 | KMT2A (0.54) | MAPTTP53KDM4EALOX15TDP1 | |
| SCHEMBL27790361 | 0.75 | ALDH1A1 (0.44) | MAPTTP53MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049325-A2 | AIR CONDITIONING SYSTEM FOR A BUILDING | BEHR GMBH & CO. KG (DE) | 2010-05-06 | — | — | WO | disclosed |
| US-7700727-B2 | Compositions and kits for detecting pathogen infection | BIOKIT, S.A. (ES) | 2010-04-20 | — | — | US | disclosed |
| WO-2009051427-A2 | A KIT FOR DIAGNOSIS OF BREAST CANCER USING HERCEPTIN, A COMPOSITION COMPRISING HERCEPTIN AND A METHOD FOR DETECTING HERCEPTIN-SENSITIVE HER2 OVEREXPRESSED CELL USING THE SAME | NATIONAL CANCER CENTER (KR) | 2009-04-23 | — | — | WO | disclosed |
| US-20060286119-A1 | Compositions and methods for treatment of chronic and infectious diseases | BIOKIT S.A. (ES) | 2006-12-21 | — | — | US | disclosed |
| US-20060275317-A1 | Vaccine compositions for prevention of chronic and infectious diseases | BIOKIT S.A. (ES) | 2006-12-07 | — | — | US | disclosed |
| US-20060269976-A1 | METHOD FOR REDUCING LYSOZYME ENZYMATIC ACTIVITY | BIOKIT S.A. (ES) | 2006-11-30 | — | — | US | disclosed |
| US-20060063149-A1 | Compositions and methods for detecting pathogen infection | Patent Administrator | 2006-03-23 | — | — | US | disclosed |
| US-20050277181-A1 | Compositions and methods for detecting pathogen infection | BIOKIT S.A. (ES) | 2005-12-15 | — | — | US | disclosed |
| US-20040142450-A1 | Lung epithelial cell line for propagating viruses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-07-22 | — | — | US | disclosed |
| WO-2002089586-A1 | LUNG EPITHELIAL CELL LINE FOR PROPAGATING VIRUSES | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063149-A1 | Compositions and methods for detecting pathogen infection | TREH, IL17A, TLL1 | MAPT 4031/4885TP53 232/4885KDM4E 4716/4885 |
| US-20060275317-A1 | Vaccine compositions for prevention of chronic and infectious diseases | IL17A, TREH, MMP17 | MAPT 3295/4885TP53 67/4885KDM4E 4722/4885 |
| US-20060269976-A1 | METHOD FOR REDUCING LYSOZYME ENZYMATIC ACTIVITY | TREH, PEPD, MMP17 | MAPT 4291/4885TP53 557/4885KDM4E 4359/4885 |
| US-20060286119-A1 | Compositions and methods for treatment of chronic and infectious diseases | IL17A, TREH, TLL1 | MAPT 3777/4885TP53 187/4885KDM4E 4813/4885 |
| US-20050277181-A1 | Compositions and methods for detecting pathogen infection | TREH, IL17A, TLL1 | MAPT 4031/4885TP53 232/4885KDM4E 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.