Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266343 | 1.00 | NAAA (0.46) | NAAATDP1MAPTKDM4ENPC1 | |
| SCHEMBL17194101 | 0.86 | NAAA (0.45) | NAAAPPARAIDH1 | |
| SCHEMBL6334745 | 0.85 | NAAA (0.57) | NAAATDP1NPC1PPARAIDH1 | |
| SCHEMBL345275 | 0.85 | NAAA (0.57) | NAAATDP1NPC1PPARAIDH1 | |
| SCHEMBL345276 | 0.85 | NAAA (0.57) | NAAATDP1NPC1PPARAIDH1 | |
| SCHEMBL7568636 | 0.83 | NAAA (0.43) | NAAAPPARAIDH1 | |
| SCHEMBL15802544 | 0.83 | NAAA (0.44) | NAAAKDM4E | |
| SCHEMBL3596515 | 0.82 | NAAA (0.43) | NAAAPPARA | |
| SCHEMBL3592578 | 0.82 | NAAA (0.43) | NAAAPPARA | |
| SCHEMBL2207671 | 0.81 | NAAA (0.53) | NAAAPPARAIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378690-A | Treatment of angiotensin induced hypertension | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0274259-B1 | New renin-inhibitory oligopeptides, their preparaton and their use | SANKYO CO (JP) | 1994-02-16 | — | — | EP | disclosed |
| EP-0274259-A2 | New renin-inhibitory oligopeptides, their preparaton and their use | Sankyo Company Limited (JP) | 1988-07-13 | — | — | EP | disclosed |