Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.43 |
| ▸ | IDH1 | O75874 | 10/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | IL6ST | P40189 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266352 | 0.83 | NAAA (0.46) | NAAAIDH1PPARA | |
| SCHEMBL7266343 | 0.83 | NAAA (0.46) | NAAAIDH1PPARA | |
| SCHEMBL345276 | 0.81 | NAAA (0.57) | NAAAIDH1FAAHPPARA | |
| SCHEMBL345275 | 0.81 | NAAA (0.57) | NAAAIDH1FAAHPPARA | |
| SCHEMBL6334745 | 0.81 | NAAA (0.57) | NAAAIDH1FAAHPPARA | |
| SCHEMBL6788947 | 0.80 | NAAA (0.51) | NAAAFAAHPPARAEP300CARM1 | |
| SCHEMBL13368994 | 0.78 | NAAA (0.50) | NAAAIDH1FAAHPPARAIL6ST | |
| SCHEMBL2207671 | 0.78 | NAAA (0.53) | NAAAIDH1FAAHPPARACSNK2B | |
| SCHEMBL292751 | 0.78 | NAAA (0.53) | NAAAIDH1FAAHPPARACSNK2B | |
| SCHEMBL292752 | 0.78 | NAAA (0.53) | NAAAIDH1FAAHPPARACSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |