Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318417 | 0.79 | CHRNA7 (0.43) | CHRNA7KDM4EALDH1A1HPGD | |
| SCHEMBL9154899 | 0.76 | CHRNA7 (0.54) | CHRNA7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9148174 | 0.75 | CHRNA7 (0.53) | CHRNA7MEN1KMT2A | |
| Oxalic Acid SCHEMBL7274627 | 0.74 | — | — | |
| SCHEMBL9448855 | 0.73 | CHRNA7 (0.49) | CHRNA7 | |
| SCHEMBL7266751 | 0.72 | CHRNA7 (0.41) | CHRNA7 | |
| SCHEMBL9150768 | 0.70 | CHRNA7 (0.42) | CHRNA7 | |
| Oxalic Acid SCHEMBL7266936 | 0.68 | CHRM2 (0.42) | CHRNA7CYP1A2CYP2C9 | |
| SCHEMBL9148599 | 0.68 | CHRNA7 (0.49) | CHRNA7 | |
| SCHEMBL7273789 | 0.67 | DHFR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328200-A1 | Five-membered ring systems with bonded azacyclic ring substituents | MERCK SHARP & DOHME LTD. (GB) | 1989-08-16 | — | — | EP | claimed |