Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275820 | 1.00 | DPP8 (0.42) | DPP8DPP7DPP4DPP9ANPEP | |
| Proline SCHEMBL7378488 | 0.88 | DPP4 (0.43) | DPP8DPP7DPP4DPP9ANPEP | |
| SCHEMBL5353931 | 0.85 | ANPEP (0.42) | DPP8DPP7DPP4DPP9ANPEP | |
| SCHEMBL3373748 | 0.85 | ANPEP (0.42) | DPP8DPP7DPP4DPP9ANPEP | |
| SCHEMBL7276985 | 0.84 | ANPEP (0.41) | DPP8DPP7DPP4DPP9ANPEP | |
| SCHEMBL7266839 | 0.81 | DPP4 (0.53) | DPP8DPP7DPP4DPP9 | |
| SCHEMBL3369068 | 0.81 | SMN1; SMN2 (0.41) | DPP8DPP7ANPEPMLYCDPOLB | |
| SCHEMBL5349213 | 0.81 | SMN1; SMN2 (0.41) | DPP8DPP7ANPEPMLYCDPOLB | |
| SCHEMBL9022605 | 0.81 | SMN1; SMN2 (0.41) | DPP8DPP7ANPEPMLYCDPOLB | |
| SCHEMBL5348541 | 0.81 | SMN1; SMN2 (0.41) | DPP8DPP7ANPEPMLYCDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1254651-A | — | — | None | — | — | JP | disclosed |
| EP-0336368-B1 | N2-(1-carboxy-3-phenylpropyl)-L-lysine derivative and process of producing lysinopril using the compound | KANEGAFUCHI CHEMICAL IND (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0336368-A2 | N2-(1-carboxy-3-phenylpropyl)-L-lysine derivative and process of producing lysinopril using the compound | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-10-11 | — | — | EP | disclosed |
| JP-H01254651-A | N2-(1-CARBOXY-3-PHENYLPROPYL)-L-LYSIN DERIVATIVE AND PRODUCTION OF LYSINOPURYL USING SAID COMPOUND | KANEGAFUCHI CHEM IND CO LTD | 1989-10-11 | — | — | JP | disclosed |