Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348541 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5349213 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9022605 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5353931 | 0.90 | ANPEP (0.42) | SMN1; SMN2POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3373748 | 0.90 | ANPEP (0.42) | SMN1; SMN2POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7276985 | 0.89 | ANPEP (0.41) | SMN1; SMN2POLBCYP1A2CYP2C9CYP2C19 | |
| Proline SCHEMBL7375209 | 0.88 | ACE (0.38) | CYP1A2CYP2C9CYP2C19HDAC3HDAC4 | |
| Proline SCHEMBL5823940 | 0.87 | ACE (0.38) | CYP1A2CYP2C9CYP2C19HDAC3HDAC4 | |
| SCHEMBL9856515 | 0.85 | KMT2A (0.43) | SMN1; SMN2POLBANPEPDPP8DPP7 | |
| SCHEMBL3368639 | 0.85 | KMT2A (0.43) | SMN1; SMN2POLBANPEPDPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239062-B1 | N2-(1-CARBOXY-3-OXO-3-PHENYLPROPYL)-L-LYSINE COMPOUNDS AND THEIR DERIVATIVES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-29 | — | — | EP | claimed |
| EP-0239062-A2 | N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-09-30 | — | — | EP | claimed |
| CN-111732627-A | Synthesis method of lisinopril impurity J | 浙江华海药业股份有限公司 | 2020-10-02 | — | — | CN | disclosed |
| EP-1679303-B1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | KANEKA CORP (JP) | 2010-09-15 | — | — | EP | disclosed |
| US-7253299-B2 | Process for purifying n2-(1(s)-ethoxycarbonyl-3-phenylpropyl)-n6-thifluoroacetyl-l-lysine | KANEKA CORPORATION (JP) | 2007-08-07 | — | — | US | disclosed |
| EP-1679303-A1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | Kaneka Corporation (JP) | 2006-07-12 | — | — | EP | disclosed |
| EP-0903337-B1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORP (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-20040147773-A1 | Process for purifying n2-(1(s)-ethoxycarbonyl -3-phenylpropyl)-n6-thifluoroacetyl-l-lysine | KANEKA CORPORATION (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1405845-A1 | METHOD FOR PURIFYING N2-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-N6-TRIFLUOROACETYL-L-LYSINE | KANEKA CORPORATION (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-0903337-A1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORPORATION (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0239062-B1 | N2-(1-CARBOXY-3-OXO-3-PHENYLPROPYL)-L-LYSINE COMPOUNDS AND THEIR DERIVATIVES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0239062-A2 | N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0239062-A2 | N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147773-A1 | Process for purifying n2-(1(s)-ethoxycarbonyl -3-phenylpropyl)-n6-thifluoroacetyl-l-lysine | KARS1, L3MBTL1, PKN2 | SMN1; SMN2 1082/4885POLB 2107/4885CYP1A2 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.