Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 11/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | UGCG | Q16739 | 3/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | AGL | P35573 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GLB1 | P16278 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267129 | 1.00 | OGA (0.38) | OGAGBA2GAAUGCGMGAM | |
| SCHEMBL29075416 | 0.94 | BCHE (0.44) | GBA2GAAUGCGGBA1BCHE | |
| SCHEMBL30168200 | 0.90 | MAOA (0.38) | GAAGBA1BCHEMAOAMAOB | |
| SCHEMBL27390238 | 0.85 | BCHE (0.38) | OGAGBA2GAAUGCGMGAM | |
| SCHEMBL8893960 | 0.85 | ATM (0.47) | OGAGBA2GAAUGCGMGAM | |
| SCHEMBL20158970 | 0.82 | MAOA (0.40) | GAAMAOAMAOBATM | |
| SCHEMBL30148983 | 0.82 | MAOA (0.40) | GAAMAOAMAOBATM | |
| SCHEMBL20158969 | 0.82 | MAOA (0.40) | GAAMAOAMAOBATM | |
| SCHEMBL16511115 | 0.81 | CYP3A4 (0.45) | OGAGBA2GAAUGCGMGAM | |
| SCHEMBL9274978 | 0.80 | ATM (0.46) | GBA2GAAUGCGGBA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346847-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 1994-05-11 | — | — | EP | disclosed |
| EP-0346847-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-20 | — | — | EP | disclosed |