Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 3/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933041 | 0.92 | ACP3 (0.54) | FNTAFNTBL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL6903558 | 0.83 | POLB (0.51) | L3MBTL1HTTSMN1; SMN2ACP3POLB | |
| SCHEMBL8125876 | 0.83 | POLB (0.51) | L3MBTL1HTTSMN1; SMN2ACP3POLB | |
| SCHEMBL7349213 | 0.83 | POLB (0.51) | L3MBTL1HTTSMN1; SMN2ACP3POLB | |
| SCHEMBL6903563 | 0.83 | POLB (0.51) | L3MBTL1HTTSMN1; SMN2ACP3POLB | |
| SCHEMBL6574775 | 0.83 | FNTA (0.54) | FNTAFNTBALDH1A1MEN1KMT2A | |
| SCHEMBL10876371 | 0.81 | FFAR1 (0.49) | FNTAFNTBL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL16933081 | 0.79 | TSHR (0.53) | L3MBTL1HTTSMN1; SMN2ACP3TP53 | |
| SCHEMBL9541616 | 0.77 | GABBR2 (0.61) | FNTAFNTBHTTSMN1; SMN2POLB | |
| SCHEMBL657290 | 0.77 | GABBR2 (0.61) | FNTAFNTBHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649613-B1 | Integrin inhibitors | MERCK PATENT GMBH (DE) | 2003-11-18 | — | — | US | disclosed |