SCHEMBL9541616

SCHEMBL9541616

O=C(O)CC(CC(=O)OC(=O)CC(CC(=O)O)c1ccccc1)c1ccccc1.O=C(O)CC(CC(=O)OC(=O)CC(CC(=O)O)c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.61
GABBR1 Q9UBS5 1/20 0.61
MAPT P10636 1/20 0.54
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4E B2RXH2 1/20 0.50
RECQL P46063 1/20 0.50
ALDH1A1 P00352 1/20 0.49
FNTA P49354 7/20 0.47
FNTB P49356 7/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
PKM P14618 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL657290 1.00 GABBR2 (0.61) GABBR2GABBR1MAPTMEN1KMT2A
SCHEMBL658940 0.90 GABBR2 (0.50) GABBR2GABBR1MAPTMEN1KMT2A
SCHEMBL503819 0.88 GABBR2 (0.76) GABBR2GABBR1MAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL7092228 0.86 GABBR2 (0.73) GABBR2GABBR1MAPTMEN1KMT2A
SCHEMBL6734410 0.86 GABBR2 (0.73) GABBR2GABBR1MAPTMEN1KMT2A
SCHEMBL12268202 0.85 ALDH1A1 (0.61) GABBR2GABBR1MAPTMEN1KMT2A
SCHEMBL1811811 0.85 ALDH1A1 (0.61) GABBR2GABBR1MAPTMEN1KMT2A
SCHEMBL657719 0.84 FNTA (0.50) GABBR2GABBR1MAPTMEN1KMT2A
SCHEMBL2471169 0.84 FNTA (0.50) GABBR2GABBR1MAPTMEN1KMT2A
SCHEMBL658678 0.84 FNTA (0.50) GABBR2GABBR1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993015093-A1 SPECIFIC CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING OF THE SMALL INTESTINE AND HEPATOBILIARY SYSTEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-08-05 WO disclosed