Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10800102 | 0.98 | MAOA (0.39) | KDM4EMAOAALDH1A1GLAMAPT | |
| SCHEMBL10715674 | 0.86 | CYP3A4 (0.41) | KDM4EMAOAALDH1A1GLAMAPT | |
| Hydrochloric Acid SCHEMBL10715838 | 0.85 | CYP3A4 (0.40) | KDM4EMAOAALDH1A1GLAMAPT | |
| SCHEMBL10710633 | 0.82 | HDAC1 (0.42) | KDM4EMAOAALDH1A1GLAMAPT | |
| SCHEMBL10711338 | 0.81 | HDAC1 (0.41) | KDM4EMAOAALDH1A1GLAMAPT | |
| SCHEMBL10711343 | 0.81 | HDAC1 (0.41) | KDM4EMAOAALDH1A1GLAMAPT | |
| SCHEMBL10439343 | 0.78 | KDM4E (0.41) | KDM4EMAOAALDH1A1GLAMAPT | |
| SCHEMBL1589841 | 0.76 | KDM4E (0.42) | KDM4EMAOAALDH1A1GLAMAPT | |
| SCHEMBL1589895 | 0.75 | KDM4E (0.41) | KDM4EMAOAALDH1A1GLAMAPT | |
| SCHEMBL28025224 | 0.75 | KDM4E (0.41) | KDM4EMAOAALDH1A1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199393-B1 | INDENE AND NAPHTHALENE DERIVATIVES | AKZO N.V. (NL) | 1988-12-07 | — | — | EP | claimed |
| US-4705782-A | Indene and naphthalene derivatives | AKZO N.V. (NL) | 1987-11-10 | — | — | US | claimed |
| EP-0352832-B1 | COMPOUNDS WITH BRONCHODILATOR ACTIVITY | AKZO N.V. (NL) | 1992-05-06 | — | — | EP | disclosed |
| US-5026724-A | Benzothiophene derivatives | AKZO N.V. (NL) | 1991-06-25 | — | — | US | disclosed |
| EP-0352832-A1 | Compounds with bronchodilator activity | AKZO N.V. (NL) | 1990-01-31 | — | — | EP | disclosed |