SCHEMBL7267353

SCHEMBL7267353

Fc1ccc(/C=N/c2ccc(Cl)cn2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.45
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 3/20 0.45
MAPT P10636 4/20 0.44
RAB9A P51151 4/20 0.44
NPC1 O15118 4/20 0.44
MEN1 O00255 3/20 0.44
ADRA2A P08913 2/20 0.42
ADRA2B P18089 2/20 0.42
ADRA2C P18825 2/20 0.42
PLAU P00749 1/20 0.42
PKM P14618 1/20 0.41
NFE2L2 Q16236 1/20 0.40
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 1/20 0.37
PTGS2 P35354 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7267356 1.00 KMT2A (0.45) KMT2AKDM4EALDH1A1MAPTRAB9A
SCHEMBL14728836 0.77 KMT2A (0.44) KMT2AKDM4EALDH1A1MAPTRAB9A
SCHEMBL19953068 0.73 CA1 (0.57) KMT2AKDM4EALDH1A1MAPTNPC1
SCHEMBL11416385 0.73 CA1 (0.57) KMT2AKDM4EALDH1A1MAPTNPC1
SCHEMBL28398293 0.73 CA1 (0.57) KMT2AKDM4EALDH1A1MAPTNPC1
SCHEMBL11416388 0.73 CA1 (0.57) KMT2AKDM4EALDH1A1MAPTNPC1
SCHEMBL7262462 0.72 RAB9A (0.55) KMT2AKDM4EALDH1A1MAPTRAB9A
SCHEMBL7262459 0.72 RAB9A (0.55) KMT2AKDM4EALDH1A1MAPTRAB9A
SCHEMBL13576459 0.72 KDM4E (0.50) KMT2AKDM4EALDH1A1MAPTRAB9A
SCHEMBL7261909 0.72 PTGS2 (0.47) KMT2AKDM4EALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6653353-B2 Hair styling anionic polymer and fluoroamines mixture improves the holding power of styling resins under high humidity conditions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-11-25 US disclosed
US-20020176834-A1 Cosmetic and personal care compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-11-28 US disclosed