Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | TLR2 | O60603 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267884 | 1.00 | CTSK (0.40) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7276468 | 0.94 | CTSK (0.40) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7278196 | 0.91 | CTSK (0.41) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7278187 | 0.91 | CTSK (0.41) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7274797 | 0.90 | TLR2 (0.40) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7274787 | 0.90 | TLR2 (0.40) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7269013 | 0.87 | CTSK (0.42) | CTSKCTSSCYP3A4MMEACE | |
| SCHEMBL7278338 | 0.87 | MMP1 (0.43) | CTSKMMETLR2MMP9MMP1 | |
| SCHEMBL7278335 | 0.87 | MMP1 (0.43) | CTSKMMETLR2MMP9MMP1 | |
| SCHEMBL7276756 | 0.87 | CTSK (0.40) | CTSKCTSSCYP3A4MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377139-B1 | N-substituted acylamino acid compounds, process for their production and their use | BANYU PHARMA CO LTD (JP) | 1995-07-12 | — | — | EP | disclosed |
| EP-0377139-A1 | N-substituted acylamino acid compounds, process for their production and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1990-07-11 | — | — | EP | disclosed |