SCHEMBL7268178

SCHEMBL7268178

Cc1n[c]cn1C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1735233 0.74 CYP11B1 (0.32) CYP11B1CYP11B2
SCHEMBL9491037 0.74 ALDH1A1 (0.33) CYP11B1CYP11B2
SCHEMBL8675355 0.73 KDM4E (0.34)
SCHEMBL17242662 0.73 HSD17B10 (0.34) CYP11B1CYP11B2
SCHEMBL8669990 0.71
SCHEMBL392779 0.68 CYP11B1 (0.43) CYP11B1CYP11B2
SCHEMBL4884756 0.68 CYP11B1 (0.35) CYP11B1CYP11B2
SCHEMBL7267261 0.67 CYP11B1 (0.38) CYP11B1CYP11B2
SCHEMBL9408078 0.67 ALDH1A1 (0.36) CYP11B1CYP11B2
SCHEMBL3500675 0.66 CYP11B1 (0.33) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866598-A 4H-CARBAZOL-4-ONES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-02-02 US disclosed
US-5698561-A PYRIDO(1,2-A)INDOLE COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-12-16 US disclosed
US-5607938-A Medicament for treating or preventing cerebrovascular infarction FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-03-04 US disclosed
EP-0361317-B1 Pyridoindole derivatives and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1995-04-05 EP disclosed
US-5290785-A Therapeutic agent for ischemic diseases FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-03-01 US disclosed
US-5173493-A For treatment or prevention of nausea or vomiting FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1992-12-22 US disclosed
US-5141945-A 5-Hydroxytryptamine antagonists, treatment or prevention of nausea and vomiting FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1992-08-25 US disclosed
EP-0361317-A2 Pyridoindole derivatives and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-04-04 EP disclosed