Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669990 | 0.76 | — | — | |
| SCHEMBL7268178 | 0.73 | CYP11B1 (0.34) | — | |
| SCHEMBL6971146 | 0.72 | KDM4E (0.37) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL17242662 | 0.65 | HSD17B10 (0.34) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7743474 | 0.63 | CYP11B1 (0.45) | — | |
| SCHEMBL3423443 | 0.63 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9491037 | 0.63 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1735233 | 0.63 | CYP11B1 (0.32) | — | |
| SCHEMBL7194664 | 0.59 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4884756 | 0.58 | CYP11B1 (0.35) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750720-A | ALPHA-ADRENORECEPTORS AND CENTRAL NERVOUS SYSTEMS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |