SCHEMBL7268305

SCHEMBL7268305

CNC(=O)[C@H](C)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cscn1)NC(=O)C(CC(=O)N1CCOCC1)Cc1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7269511 1.00 REN (0.82) REN
SCHEMBL7268300 1.00 REN (0.82) REN
SCHEMBL7270076 0.94 REN (0.80) REN
SCHEMBL7270226 0.94 REN (0.80) REN
SCHEMBL7270080 0.94 REN (0.80) REN
SCHEMBL7269251 0.92 REN (0.76) REN
SCHEMBL7269257 0.92 REN (0.76) REN
SCHEMBL7277384 0.92 REN (0.76) REN
SCHEMBL7327981 0.92 REN (0.76) REN
SCHEMBL7327974 0.92 REN (0.76) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383635-B1 Peptides having renin inhibitory activity their preparation and use SANKYO CO (JP) 1995-07-12 — — EP claimed
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