SCHEMBL7270080

SCHEMBL7270080

CNC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cscn1)NC(=O)C(CC(=O)N1CCOCC1)Cc1ccccc1)C(C)C

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270076 1.00 REN (0.80) REN
SCHEMBL7270226 1.00 REN (0.80) REN
SCHEMBL7268305 0.94 REN (0.82) REN
SCHEMBL7268300 0.94 REN (0.82) REN
SCHEMBL7269511 0.94 REN (0.82) REN
SCHEMBL7270369 0.93 REN (0.69) REN
SCHEMBL7279339 0.93 REN (0.69) REN
SCHEMBL7270374 0.93 REN (0.69) REN
SCHEMBL7277408 0.92 REN (0.75) REN
SCHEMBL7269381 0.92 REN (0.75) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383635-B1 Peptides having renin inhibitory activity their preparation and use SANKYO CO (JP) 1995-07-12 — — EP claimed
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