Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 3/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268787 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MMEECE1FOLH1LMNA | |
| SCHEMBL7126845 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MMEECE1FOLH1LMNA | |
| SCHEMBL8765302 | 0.78 | FOLH1 (0.50) | ALDH1A1FOLH1LMNAPOLBHSD17B10 | |
| SCHEMBL6849355 | 0.78 | FOLH1 (0.50) | ALDH1A1FOLH1LMNAPOLBHSD17B10 | |
| SCHEMBL8765293 | 0.78 | FOLH1 (0.50) | ALDH1A1FOLH1LMNAPOLBHSD17B10 | |
| SCHEMBL3402177 | 0.75 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1TDP1KMT2A | |
| SCHEMBL8020376 | 0.74 | FOLH1 (0.41) | ALDH1A1MMEECE1FOLH1SLC1A3 | |
| SCHEMBL29395689 | 0.74 | MME (0.38) | ALDH1A1MMEECE1FOLH1L3MBTL1 | |
| SCHEMBL27604114 | 0.74 | FOLH1 (0.40) | ALDH1A1MMEECE1FOLH1L3MBTL1 | |
| SCHEMBL18343735 | 0.74 | MME (0.38) | ALDH1A1MMEECE1FOLH1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656937-B2 | Immunology moderators; interleukin antagonist; anticancer agents | GRUENENTHAL, GMBH (DE) | 2003-12-02 | — | — | US | disclosed |