SCHEMBL2097101

SCHEMBL2097101

[N].c1cnc2c(c1)ccc1ncccc12

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.96
▸ CYP3A4 P08684 2/20 0.64
▸ CCR1 P32246 5/20 0.60
▸ CCR8 P51685 5/20 0.60
▸ MAPT P10636 3/20 0.60
▸ HSP90AA1 P07900 3/20 0.60
▸ CCR5 P51681 3/20 0.60
▸ KDM4E B2RXH2 2/20 0.60
▸ HTT P42858 2/20 0.60
▸ HIF1A Q16665 2/20 0.60
▸ MMP2 P08253 2/20 0.60
▸ TSHR P16473 2/20 0.60
▸ GMNN O75496 1/20 0.60
▸ TP53 P04637 1/20 0.60
▸ CYP2D6 P10635 1/20 0.60
▸ MMP9 P14780 1/20 0.60
▸ ALOX15 P16050 1/20 0.60
▸ NFKB1 P19838 1/20 0.60
▸ MMP8 P22894 1/20 0.60
▸ THPO P40225 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8313 0.98 LMNA (1.00) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL6513577 0.98 LMNA (1.00) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL1681333 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL14576748 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL8728454 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL1003398 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL15052618 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL722331 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL4447950 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL4858817 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080422-A Aluminum-iron dissimilar metal organic framework material and preparation method and application thereof — 2026-05-26 — — CN disclosed
CN-122080422-A Aluminum-iron dissimilar metal organic framework material and preparation method and application thereof — 2026-05-26 — — CN disclosed
CN-119751468-A Preparation method of qianli feilidine oxynitride 成都普思生物科技股份有限公司 2025-04-04 — — CN disclosed
CN-118530262-A Linear terpyridine Cu complex and preparation method and application thereof 苏州大学附属儿童医院 2024-08-23 — — CN disclosed
CN-117417357-A Chiral phenanthroline-dinitrogen oxygen ligand, intermediate, preparation method thereof and application thereof in asymmetric catalytic reaction 贵州大学 2024-01-19 — — CN disclosed
CN-116459856-A High-stability catalyst for hydrochlorination of acetylene as well as preparation method and application thereof 鄂尔多斯市瀚博科技有限公司 2023-07-21 — — CN disclosed
US-20230102826-A1 HEPARANASE INHIBITORS FOR TREATMENT OF DIABETES WAYNE STATE UNIVERSITY (US) 2023-03-30 — — US disclosed
US-11524026-B2 Heparanase inhibitors for treatment of diabetes WAYNE STATE UNIVERSITY (US) 2022-12-13 — — US disclosed
CN-114133406-A Conjugated organic complex of europium (III) and preparation method and application thereof 南京邮电大学 2022-03-04 — — CN disclosed
US-11179710-B2 Direct palladium-catalyzed aromatic fluorination PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-11-23 — — US disclosed
US-9714441-B2 Mediator-stabilized reagent compositions for use in biosensor electrodes ABBOTT DIABETES CARE INC. (US) 2017-07-25 — — US disclosed
WO-2016004156-A1 COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR TREATMENT OF CANCERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-01-07 — — WO disclosed
US-20140216949-A1 Mediator-Stabilized Reagent Compositions for Use in Biosensor Electrodes ABBOTT DIABETES CARE INC. (US) 2014-08-07 — — US disclosed
US-8696884-B2 Mediator stabilized reagent compositions for use in biosensor electrodes ABBOTT DIABETES CARE INC. (US) 2014-04-15 — — US disclosed
US-20120325679-A1 Mediator-Stabilized Reagent Compositions for Use in Biosensor Electrodes ABBOTT DIABETES CARE INC. 2012-12-27 — — US disclosed
US-8163146-B2 Mediator stabilized reagent compositions for use in biosensor electrodes ABBOTT DIABETES CARE INC. (US) 2012-04-24 — — US disclosed
EP-2205713-A1 MEDIATOR-STABILIZED REAGENT COMPOSITIONS FOR USE IN BIOSENSOR ELECTRODES Abbott Diabetes Care, Inc. (US) 2010-07-14 — — EP disclosed
US-20090095625-A1 Mediator-Stabilized Reagent Compositions for Use in Biosensor Electrodes ABBOTT DIABETES CARE INC. 2009-04-16 — — US disclosed
WO-2009049093-A1 MEDIATOR-STABILIZED REAGENT COMPOSITIONS FOR USE IN BIOSENSOR ELECTRODES ABBOTT DIABETES CARE INC. (US) 2009-04-16 — — WO disclosed
US-20080206890-A1 BIS(2,9-DI-TERT-BUTYL-1,10-PHENANTHROLINE)COPPER(I) COMPLEXES, METHODS OF SYNTHESIS, AND USES THEROF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080206890-A1 BIS(2,9-DI-TERT-BUTYL-1,10-PHENANTHROLINE)COPPER(I) COMPLEXES, METHODS OF SYNTHESIS, AND USES THEROF TTI1, TTI2, TCOF1 LMNA 2087/4885CYP3A4 4004/4885CCR1 2095/4885
US-11524026-B2 Heparanase inhibitors for treatment of diabetes HPSE, ENGASE, HEXD LMNA 2549/4885CYP3A4 1785/4885CCR1 1430/4885
US-11179710-B2 Direct palladium-catalyzed aromatic fluorination KRAS, NRAS, DDT LMNA 4383/4885CYP3A4 959/4885CCR1 1353/4885
US-20230102826-A1 HEPARANASE INHIBITORS FOR TREATMENT OF DIABETES HPSE, ENGASE, HEXD LMNA 2549/4885CYP3A4 1785/4885CCR1 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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