Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269124 | 1.00 | REN (0.41) | RENCTSSCTSKCYP3A4ALDH1A1 | |
| SCHEMBL7267650 | 0.91 | REN (0.43) | RENCTSSCTSKALDH1A1TSHR | |
| SCHEMBL7278341 | 0.87 | CTSK (0.42) | RENCTSSCTSKCYP3A4MME | |
| SCHEMBL7278347 | 0.87 | CTSK (0.42) | RENCTSSCTSKCYP3A4MME | |
| SCHEMBL7278196 | 0.86 | CTSK (0.41) | RENCTSSCTSKCYP3A4MME | |
| SCHEMBL7278187 | 0.86 | CTSK (0.41) | RENCTSSCTSKCYP3A4MME | |
| SCHEMBL7269058 | 0.85 | CTSK (0.41) | RENCTSSCTSKCYP3A4MME | |
| SCHEMBL7269132 | 0.85 | CTSK (0.41) | RENCTSSCTSKCYP3A4MME | |
| SCHEMBL7269141 | 0.85 | CTSK (0.41) | RENCTSSCTSKCYP3A4MME | |
| SCHEMBL7269047 | 0.85 | CTSK (0.41) | RENCTSSCTSKCYP3A4MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377139-B1 | N-substituted acylamino acid compounds, process for their production and their use | BANYU PHARMA CO LTD (JP) | 1995-07-12 | — | — | EP | disclosed |
| EP-0377139-A1 | N-substituted acylamino acid compounds, process for their production and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1990-07-11 | — | — | EP | disclosed |