Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5902814 | 0.81 | DDB1 (0.44) | DDB1CRBNALDH1A1 | |
| SCHEMBL29845330 | 0.77 | ALDH1A1 (0.45) | DDB1CRBNALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL3887001 | 0.77 | ALDH1A1 (0.45) | DDB1CRBNALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL743375 | 0.77 | DDB1 (0.42) | DDB1CRBNALDH1A1CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6543327 | 0.76 | ALDH1A1 (0.44) | DDB1CRBNALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19176803 | 0.76 | ALDH1A1 (0.50) | DDB1CRBNALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL10476664 | 0.74 | CYP3A4 (0.49) | DDB1CRBNALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL32674110 | 0.74 | ALDH1A1 (0.50) | DDB1CRBNALDH1A1CYP2C19KMT2A | |
| SCHEMBL17162725 | 0.74 | DDB1 (0.44) | DDB1CRBNALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL17162699 | 0.73 | DDB1 (0.43) | DDB1CRBNALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270557-B1 | ETHYLENEDIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-1270557-A1 | ETHYLENEDIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |