Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742955 | 0.79 | DDB1 (0.47) | DDB1CRBNALDH1A1KMT2ACA12 | |
| SCHEMBL19176803 | 0.79 | ALDH1A1 (0.50) | DDB1CRBNCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL742006 | 0.78 | DDB1 (0.43) | DDB1CRBNCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7269176 | 0.77 | DDB1 (0.40) | DDB1CRBNCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL17162725 | 0.76 | DDB1 (0.44) | DDB1CRBNCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL741732 | 0.76 | ALDH1A1 (0.51) | DDB1CRBNCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL17162699 | 0.75 | DDB1 (0.43) | DDB1CRBNCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL24516624 | 0.74 | DDB1 (0.42) | DDB1CRBNCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL21504136 | 0.74 | DDB1 (0.47) | DDB1CRBNCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2542693 | 0.73 | DDB1 (0.54) | DDB1CRBNCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-B1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI SANKYO CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |