Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275363 | 1.00 | CA2 (0.36) | CA2SLC6A2SLC6A4CACNA2D1CTSA | |
| SCHEMBL21962291 | 0.85 | CA2 (0.35) | CA2SLC6A2SLC6A4CACNA2D1 | |
| SCHEMBL9096637 | 0.80 | CA2 (0.31) | CA2SLC6A2SLC6A4 | |
| SCHEMBL2161823 | 0.75 | CES1 (0.41) | CA2SLC6A2SLC6A4LMNA | |
| SCHEMBL4921120 | 0.74 | KDM4E (0.32) | CTSAKDM4ELMNA | |
| SCHEMBL9096865 | 0.73 | CNR2 (0.31) | KDM4E | |
| SCHEMBL21962093 | 0.71 | CTSA (0.32) | CTSA | |
| SCHEMBL6672449 | 0.69 | — | — | |
| SCHEMBL1975745 | 0.68 | FBP1 (0.39) | SLC6A2SLC6A4CTSAFBP1KDM4E | |
| SCHEMBL9095403 | 0.68 | SLC6A2 (0.36) | CA2SLC6A2SLC6A4CACNA2D1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |