Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722546 | 0.89 | NPY5R (0.41) | NPY5RL3MBTL3LTA4HMCHR1 | |
| SCHEMBL13803962 | 0.86 | NPY5R (0.47) | NPY5REPHX2EPHX1L3MBTL3CYP1A2 | |
| SCHEMBL26683504 | 0.82 | L3MBTL3 (0.40) | NPY5RL3MBTL3SMN1; SMN2 | |
| SCHEMBL4550247 | 0.81 | L3MBTL3 (0.58) | NPY5REPHX2EPHX1L3MBTL3CYP1A2 | |
| SCHEMBL19542249 | 0.79 | NPY5R (0.43) | NPY5REPHX2EPHX1 | |
| SCHEMBL13478878 | 0.79 | NPY5R (0.43) | NPY5REPHX2EPHX1L3MBTL3CYP1A2 | |
| SCHEMBL19419455 | 0.79 | NPY5R (0.43) | NPY5REPHX2EPHX1L3MBTL3KIF11 | |
| SCHEMBL19710577 | 0.79 | KDM4E (0.45) | NPY5REPHX2EPHX1L3MBTL3CYP1A2 | |
| SCHEMBL14997483 | 0.79 | EPHX2 (0.43) | NPY5REPHX2EPHX1L3MBTL3CYP1A2 | |
| SCHEMBL8282498 | 0.79 | ALDH1A1 (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457686-B1 | Novel aminopiperidine, aminopyrrolidine and aminoperhydroazepine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-08-03 | — | — | EP | disclosed |
| EP-0457686-A1 | Novel aminopiperidine, aminopyrrolidine and aminoperhydroazepine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-11-21 | — | — | EP | disclosed |