Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269017 | 0.87 | DRD2 (0.50) | DRD2LMNA | |
| SCHEMBL7275959 | 0.87 | DRD2 (0.38) | DRD2ALDH1A1HPGDHSD17B10MYC | |
| SCHEMBL7268995 | 0.83 | SLC5A2 (0.44) | DRD2MYCAKR1C3MAPT | |
| SCHEMBL7278170 | 0.83 | DRD2 (0.46) | DRD2 | |
| SCHEMBL7274861 | 0.82 | DRD2 (0.51) | DRD2MYCNR4A1NOTUMAKR1C4 | |
| Hydrochloric Acid SCHEMBL7270776 | 0.81 | DRD2 (0.50) | DRD2MYCNR4A1NOTUMAKR1C4 | |
| SCHEMBL7270656 | 0.80 | DRD2 (0.52) | DRD2ALDH1A1MAPT | |
| SCHEMBL7270723 | 0.80 | GAA (0.40) | DRD2ALDH1A1HPGDHTTMAPT | |
| SCHEMBL7268755 | 0.80 | MAPT (0.43) | ALDH1A1MAPT | |
| SCHEMBL7275808 | 0.80 | NOTUM (0.53) | DRD2NOTUMAKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |