Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278170 | 0.89 | DRD2 (0.46) | DRD2SLC5A2TSHR | |
| SCHEMBL7271086 | 0.83 | MAPT (0.44) | DRD2ALDH1A1SIGMAR1MAPTNAAA | |
| SCHEMBL7268995 | 0.82 | SLC5A2 (0.44) | DRD2SLC5A2MAPTNAAATSHR | |
| SCHEMBL7269017 | 0.81 | DRD2 (0.50) | DRD2SIGMAR1 | |
| SCHEMBL7278312 | 0.81 | CYP1A2 (0.45) | DRD2ADRA1DMAPT | |
| SCHEMBL7269453 | 0.80 | DRD2 (0.41) | DRD2ALDH1A1MAPT | |
| SCHEMBL7270723 | 0.79 | GAA (0.40) | DRD2SLC5A2ALDH1A1MAPTTSHR | |
| SCHEMBL9488302 | 0.79 | DRD2 (0.40) | DRD2SLC5A2ADRA1DALDH1A1ALDH2 | |
| SCHEMBL7275959 | 0.78 | DRD2 (0.38) | DRD2ALDH1A1 | |
| SCHEMBL7268755 | 0.76 | MAPT (0.43) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |