Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 14/20 | 0.81 |
| ▸ | FAAH | O00519 | 5/20 | 0.79 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661775 | 0.90 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19612683 | 0.88 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19612722 | 0.88 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19612734 | 0.88 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL16337701 | 0.84 | NAAA (0.83) | NAAAFAAH | |
| SCHEMBL28703216 | 0.81 | NAAA (0.64) | NAAAFAAH | |
| SCHEMBL19423249 | 0.79 | NAAA (0.68) | NAAAFAAH | |
| SCHEMBL20902271 | 0.79 | NAAA (0.62) | NAAAFAAH | |
| SCHEMBL19774963 | 0.78 | NAAA (0.70) | NAAAFAAH | |
| SCHEMBL17413866 | 0.78 | NAAA (0.56) | NAAAFAAHFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512415-B1 | Process for the enantioselective synthesis of 2(R)-benzyl succanamide derivatives | HOECHST AG (DE) | 1997-08-06 | — | — | EP | disclosed |
| EP-0383635-B1 | Peptides having renin inhibitory activity their preparation and use | SANKYO CO (JP) | 1995-07-12 | — | — | EP | disclosed |
| US-5321139-A | Amination of phenylitaconic anhydride, catalytic reduction of formed amide; renin inhibitor | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-14 | — | — | US | disclosed |
| EP-0512415-A2 | Process for the enantioselective synthesis of 2(R)-benzyl succanamide derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0383635-A2 | Peptides having renin inhibitory activity their preparation and use | Sankyo Company Limited (JP) | 1990-08-22 | — | — | EP | disclosed |