Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 12/20 | 0.83 |
| ▸ | FAAH | O00519 | 8/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612649 | 0.91 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19612527 | 0.87 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19612567 | 0.87 | FAAH (1.00) | NAAAFAAH | |
| SCHEMBL19612588 | 0.87 | FAAH (1.00) | NAAAFAAH | |
| SCHEMBL28703216 | 0.84 | NAAA (0.64) | NAAAFAAH | |
| SCHEMBL16335626 | 0.84 | FAAH (0.61) | NAAAFAAHALDH1A1HSD11B1 | |
| SCHEMBL5175174 | 0.84 | FAAH (0.61) | NAAAFAAHALDH1A1HSD11B1 | |
| SCHEMBL7269558 | 0.84 | NAAA (0.81) | NAAAFAAH | |
| SCHEMBL19612661 | 0.84 | FAAH (1.00) | NAAAFAAHALDH1A1 | |
| SCHEMBL19612755 | 0.82 | NAAA (1.00) | NAAAFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3214086-B1 | SUBSTITUTED DIHYDROPYRROLOPYRAZOLE COMPOUND | UBE INDUSTRIES (JP) | 2021-09-22 | — | — | EP | disclosed |
| US-10968238-B2 | Substituted dihydropyrrolopyrazole compound | UBE INDUSTRIES, LTD. (JP) | 2021-04-06 | — | — | US | disclosed |
| CN-107074788-B | Substituted heterocyclic derivatives, preparation method and application thereof | 厦门大学 | 2019-09-20 | — | — | CN | disclosed |
| US-10131679-B2 | Substituted dihydropyrrolopyrazole compound | UBE INDUSTRIES, LTD. (JP) | 2018-11-20 | — | — | US | disclosed |
| US-20170313727-A1 | SUBSTITUTED DIHYDROPYRROLOPYRAZOLE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2017-11-02 | — | — | US | disclosed |
| EP-3214086-A1 | SUBSTITUTED DIHYDROPYRROLOPYRAZOLE COMPOUND | Ube Industries, Ltd. (JP) | 2017-09-06 | — | — | EP | disclosed |
| US-9598383-B2 | Reactive oxygen species-based prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-21 | — | — | US | disclosed |
| CN-104356082-B | One class substituted heterocycle derivant and preparation method thereof | 厦门大学 | 2016-07-13 | — | — | CN | disclosed |
| CN-104356082-A | Substituted heterocyclic derivative and preparation method thereof | UNIV XIAMEN | 2015-02-18 | — | — | CN | disclosed |
| US-20150005352-A1 | REACTIVE OXYGEN SPECIES-BASED PRODRUGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005352-A1 | REACTIVE OXYGEN SPECIES-BASED PRODRUGS | ROS1, NOX4, NOX1 | NAAA 2323/4885FAAH 4085/4885ALDH1A1 173/4885 |
| US-20170313727-A1 | SUBSTITUTED DIHYDROPYRROLOPYRAZOLE COMPOUND | QDPR, CYP2D6, DCLK3 | NAAA 3083/4885FAAH 3415/4885ALDH1A1 246/4885 |
| US-10131679-B2 | Substituted dihydropyrrolopyrazole compound | QDPR, CYP2D6, DCLK3 | NAAA 3083/4885FAAH 3415/4885ALDH1A1 246/4885 |
| US-10968238-B2 | Substituted dihydropyrrolopyrazole compound | QDPR, CYP2D6, KCNJ11 | NAAA 2866/4885FAAH 3242/4885ALDH1A1 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.