Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824420 | 1.00 | MAPT (0.66) | MAPTALDH1A1PKMHTTL3MBTL1 | |
| SCHEMBL11926985 | 0.82 | ALDH1A1 (0.73) | MAPTALDH1A1PKMHTTL3MBTL1 | |
| SCHEMBL2404979 | 0.81 | AKR1C3 (0.47) | MAPTALDH1A1PKMHTTL3MBTL1 | |
| SCHEMBL2404976 | 0.81 | AKR1C3 (0.47) | MAPTALDH1A1PKMHTTL3MBTL1 | |
| SCHEMBL30352917 | 0.80 | MAPT (0.53) | MAPTALDH1A1PKMHTTL3MBTL1 | |
| SCHEMBL30352913 | 0.80 | MAPT (0.53) | MAPTALDH1A1PKMHTTL3MBTL1 | |
| SCHEMBL20163177 | 0.78 | ALDH1A1 (0.63) | MAPTALDH1A1PKMHTTL3MBTL1 | |
| SCHEMBL8824439 | 0.78 | CYP1A2 (0.51) | MAPTALDH1A1PKMHTTL3MBTL1 | |
| SCHEMBL8824441 | 0.78 | CYP1A2 (0.51) | MAPTALDH1A1PKMHTTL3MBTL1 | |
| SCHEMBL12101425 | 0.77 | TSHR (0.54) | MAPTALDH1A1PKMHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665763-A | ANTIPICORNAVIRAL AGENTS | SANOFI, S.A. (FR) | 1997-09-09 | — | — | US | disclosed |
| US-5567717-A | COMBATTING PICORNAVIRUSES | STERLING WINTHROP, INC. (US) | 1996-10-22 | — | — | US | disclosed |
| US-5514679-A | TREATMENT OF PICORNAVIRUS INFECTIONS | STERLING WINTHROP INC. (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1995031439-A1 | THERAPEUTIC PHENOXYALKYLPYRIDAZINES AND INTERMEDIATES THEREFOR | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |