Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | PKM | P14618 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176817 | 0.86 | MAPT (0.54) | ALDH1A1MAPTL3MBTL1PKMHTT | |
| SCHEMBL11926985 | 0.84 | ALDH1A1 (0.73) | ALDH1A1MAPTL3MBTL1PKMHTT | |
| SCHEMBL20163174 | 0.79 | MAPT (0.54) | ALDH1A1MAPTL3MBTL1PKMHTT | |
| SCHEMBL7269702 | 0.78 | MAPT (0.66) | ALDH1A1MAPTL3MBTL1PKMHTT | |
| SCHEMBL8824420 | 0.78 | MAPT (0.66) | ALDH1A1MAPTL3MBTL1PKMHTT | |
| SCHEMBL16159991 | 0.78 | MAPT (0.50) | ALDH1A1MAPTL3MBTL1PKMHTT | |
| SCHEMBL20163172 | 0.77 | MEN1 (0.56) | ALDH1A1MAPTL3MBTL1PKMHTT | |
| SCHEMBL30352917 | 0.74 | MAPT (0.53) | ALDH1A1MAPTL3MBTL1PKMHTT | |
| SCHEMBL30352913 | 0.74 | MAPT (0.53) | ALDH1A1MAPTL3MBTL1PKMHTT | |
| SCHEMBL8039305 | 0.73 | GLO1 (1.00) | ALDH1A1MAPTL3MBTL1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | claimed |
| US-10561594-B2 | Agent for stabilizing keratin fibers with 5-ring heterocycles | HENKEL AG & CO. KGAA (DE) | 2020-02-18 | — | — | US | disclosed |
| US-10561594-B2 | Agent for stabilizing keratin fibers with 5-ring heterocycles | HENKEL AG & CO. KGAA (DE) | 2020-02-18 | — | — | US | disclosed |
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | KRT18, NDUFS5, NDUFA5 | ALDH1A1 992/4885MAPT 1624/4885L3MBTL1 4794/4885 |
| US-10561594-B2 | Agent for stabilizing keratin fibers with 5-ring heterocycles | KRT18, NDUFS5, NDUFA5 | ALDH1A1 992/4885MAPT 1624/4885L3MBTL1 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.