Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595455 | 0.87 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL9868324 | 0.84 | AGTR1 (0.63) | AGTR1 | |
| SCHEMBL9207107 | 0.81 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL9212989 | 0.80 | AGTR1 (0.57) | AGTR1 | |
| SCHEMBL7279598 | 0.79 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL8954136 | 0.78 | AGTR1 (0.62) | AGTR1 | |
| SCHEMBL9205161 | 0.77 | AGTR1 (0.54) | AGTR1 | |
| SCHEMBL8954193 | 0.76 | — | — | |
| SCHEMBL8954188 | 0.76 | — | — | |
| SCHEMBL9367614 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955294-A2 | Imidazolyl-alkenoic acid | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5418250-A | Hypotensive | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-23 | — | — | US | disclosed |
| US-5185351-A | Hypotensive agents; for treatment of congestive heart failure, renal failure and glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |