SCHEMBL9868324

SCHEMBL9868324

CCCCc1ncc(CC(C)(Cc2cccs2)C(=O)O)n1Cc1ccccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9207107 0.87 AGTR1 (0.58) AGTR1
SCHEMBL9212989 0.86 AGTR1 (0.57) AGTR1
SCHEMBL7269794 0.84 AGTR1 (0.58) AGTR1
SCHEMBL9205161 0.82 AGTR1 (0.54) AGTR1
SCHEMBL8954136 0.82 AGTR1 (0.62) AGTR1
SCHEMBL7275546 0.80 AGTR1 (0.79) AGTR1
SCHEMBL7275553 0.80 AGTR1 (0.79) AGTR1
SCHEMBL7059057 0.79
SCHEMBL8534004 0.79 AGTR1 (0.59) AGTR1
SCHEMBL9454059 0.78 AGTR1 (0.58) AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3115278-A None JP disclosed
JP-H03115278-A IMIDAZOLYL ALKENOIC ACID SMITHKLINE BEECHAM CORP 1991-05-16 JP disclosed