Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079540 | 0.87 | ALDH1A1 (0.50) | ALDH1A1SOAT1THRBATML3MBTL1 | |
| SCHEMBL1078000 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SOAT1THRBATML3MBTL1 | |
| SCHEMBL7632452 | 0.80 | CYP19A1 (0.44) | ALDH1A1SOAT1THRBATML3MBTL1 | |
| SCHEMBL29315096 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SOAT1THRBATML3MBTL1 | |
| SCHEMBL29315120 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SOAT1THRBATML3MBTL1 | |
| SCHEMBL3744068 | 0.78 | CHRM2 (0.46) | ALDH1A1THRBKMT2AEPHX1CHRM2 | |
| SCHEMBL2498680 | 0.78 | CHRM2 (0.46) | ALDH1A1THRBKMT2AEPHX1CHRM2 | |
| SCHEMBL1077452 | 0.78 | ALDH1A1 (0.44) | ALDH1A1SOAT1THRBATML3MBTL1 | |
| SCHEMBL1079229 | 0.77 | ALDH1A1 (0.40) | ALDH1A1SOAT1THRBATML3MBTL1 | |
| SCHEMBL1080228 | 0.77 | EPHX1 (0.50) | ALDH1A1SOAT1THRBATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |